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Jackie Twu (Often misspelt as Jackie Two, or Jackie 2), is the unloved son of Jackie Chu. He first appears in The Fly Problem!. He was two years old and he has 2 PHD's in Calculus. He makes iPads with his siblings for Mainland China. Jackie Twu was voiced by Chilly in The Fly Problem! Then he was voiced by Chris in later episodes.
- Unlike Jackie Chu, Jackie Twu does not have slanted eyes, because according to Jackie Chu, he doesn't go into puberty until he's 13 years old.
- He has no time for friends. Just work.
- Jackie Twu is the 2nd most intelligent character in SML since he is only 3 and has 2 PhDs in Calculus. He is listed as the 2nd most intelligent character in the List of character attribute rankings.